What does the prefix 'Epi-' refer to?

The prefix 'Epi-' derives from Greek origins, meaning "above" or "upon." In medical terminology, it is often used to describe structures or conditions that are situated on the surface or above a particular body part. For instance, the term 'epidermis' refers to the outer layer of skin, which is literally 'upon' or 'above' the underlying layers. This prefix helps provide clarity in describing anatomical relationships or locations, making it essential for understanding various medical terms. The meanings of the other prefixes do not align with the definition of 'epi,' demonstrating the importance of distinguishing between different prefixes in medical vocabulary.