Which medical procedure is primarily used to identify the presence of disease in a sample of tissue?

The procedure primarily used to identify the presence of disease in a sample of tissue is a biopsy. A biopsy involves taking a small piece of tissue from a patient and sending it to a laboratory for examination. This process allows healthcare providers to determine whether the tissue is healthy or contains abnormal (diseased) cells. The findings from a biopsy can be pivotal in diagnosing conditions such as cancer, infections, or inflammatory diseases.

In contrast, a pathology assessment refers to the comprehensive evaluation conducted by a pathologist, which may involve multiple types of tissue evaluations, but it is not a standalone procedure for obtaining tissue samples. Histology examination specifically looks at the microscopic structure of tissues, which often employs samples obtained through biopsies. Diagnosis assembly is not a recognized medical procedure; it suggests the process of compiling various diagnostic information, rather than directly identifying disease through tissue sampling. Thus, the biopsy stands out as the key procedure specifically associated with obtaining tissue to diagnose diseases.